ProEnt2

GASTROINTESTINAL CLEANSER
Utilizing the Power of Essential Oils

Antimicrobial Oils
Evidence is now building that certain plant oils may have profound effects against a wide range of infective agents, e.g. in independent studies, a mixture of oregano leaf, artemesia leaf, ginger grass, cloves and grapeseed oils has been shown to prevent the proliferation of a variety of important bacteria, even when up to 20,000 fold. See table below and Fig. 1.

These types of oil products are likely to play an increasing role in health maintenance over the next several years, especially as the level of resistance to antibiotics continues to increase. Research on the use of these types of oils continues.

Natural Systemic Approach
A natural systemic approach that avoids drug use. Fungal proliferation has generally fallen into two categories.

  1. Local: Mucosal overgrowth within the intestinal tract.
  2. Systemic: Fungal overgrowth of Candida albicans that has migrated beyond the confines of the bowel throughout the intestinal tract and to distal sites around the body, causing an antigen challenge and peripheral reactions.

Current Systemic Approaches
To date, the only truly effective antifungals that have extraintestinal action against systemic yeast are prescription only drugs. While the majority of these are able to eradicate Candida albicans throughout the body, they are also characterized by a marked degree of toxicity, particularly affecting liver and kidney function, especially if used over a long period. Furthermore, some of these drugs have an adverse effect upon the intestinal microflora, the friendly bacteria, thus increasing the source of the problem they are attempting to eradicate.

Natural Approach
Scientists have now focused their attention upon a new series of natural compounds extracted from various plants such as extracts from oregano leaf, artemesia leaf, ginger grass, cloves and grapeseed oils which have a potent systemic effect against all yeast organisms. The drawback up until now in using these substances has been their stability. The extracts are inherently very unstable and oxidize quickly. They lose potency and become ineffective against microbes.

The New Alternative
It is very difficult to obtain maximum benefit from currently available liquid oil supplement for several reasons including:

  1. Oxidative damage in vitro and vivo
  2. Poor absorption of liquid oils
  3. Poor dispersion and spatial targeting of antimicrobial liquid oils

To solve these problems there are different technologies used to provide freeze dried, fully micellized, microencapsulated and oxidation resistant, antimicrobial botanical oils. Then the ingredients can be efficiently absorbed and fully dispersible in the water based environment of the body to target microorganisms. This combination is an excellent adjunct in health maintenance against microbes, especially as the level of resistance to antibiotics continues to increase.

University Study
In vitro study performed at University of Woverhampton, Dept. Microbiology, U.K., on antimicrobial combination.

Summary: The following organisms were tested for Minimum Inhibitory (MIC) and Minimal Microbicidal (MBC) activity. Organisms Tested:

  • Candida albicans, 3 clinical isolates
  • Campylobacter jejuni, 3 strains
  • Salmonella typhirum
  • Helicobacter pylori, 2 clinical isolates
  • Escherichia coli, 3 strains

Summary of Study on Antimicrobial Activity

Organism MIC MBC
Escherichia coli, 3 strains 1.6-2.5 mg/ml 2.5-10 mg/ml
Salmonella typhirium 2.505 mg/ml 5-10 mg/ml
Campylobacter jejuni, 3 strains 1.25-5 mg/ml 1.25-5 mg/ml
Candida albicans, 3 clinical isolates 1.25-2.5 mg/ml 2.5 mg/ml
Helicobacter pylori, 2 clinical isolates 9.5-156 mg/ml 19-156 mg/ml

Please note the activity against H. pylori is in mg (micrograms) per ml. The combination of antimicrobial oils activity falls in the same range as that of pharmaceutical preparations (antibiotics), 15-50mg/ml.

Evidence is now building that certain plant oils may have profound effects against a wide range of infective agents, e.g. in independent studies, a mixture of oregano leaf, artemesia leaf, ginger grass, cloves and grapeseed oils has been shown to prevent the proliferation of a variety of important bacteria, even when diluted up to 20,000 fold.


 

 

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