Logic of Bone Support
Maintaining bone health is a complex and multifactorial issue that must
focus on optimizing conditions in the micro-architectural environment
of bones. Two facets must be considered in maintaining bone integrity.
Oss Aide™ Doses
VITAMIN K
Oss Aide™ contains a very generous amount of Vitamin K1, a
crucial component to bone health; Oss Aide™ provides 20 times
the RDA of Vitamin K1 as a water soluble form with an absorption >
70%. In contrast, the absorption of pure form fat soluble Vitamin K1 is
40% or less. Vitamin K1 in foods has an even lower bioavailability.
To obtain the same amount of Vitamin K1 found in Oss Aid™ a person would need to eat: 300 apples or 4lbs of liver meat or 200 cups of cows milk or 1.5 lbs of spinach or 7 lbs of tomatoes or 3 lbs of broccoli or 1 lb of cauliflower.
Furthermore, the nutritional significance of Vitamin K produced by colonic bacteria is not clear, and colonic absorption of bacterial menaquinones (Vitamin K forms) is less than 10% at best. Vitamin K1 doses > 10mg/day have been shown to have no side effects.
In summary, the average diet provides meager amounts of Vitamin K1, <100 micrograms/day and less than half of it is bioavailable.
CALCIUM/MAGNESIUM
The 1200mg daily calcium and 400mg of magnesium intake recommendations
are targeted towards creating a 20:1 calcium/protein and a 3:1 calcium/magnesium
ration; assuming a fractional absorption for calcium and magnesium of
28-33%. Thus, if you consume the average 60 grams of protein a day, you
will need 1200mg of calcium and 400mg magnesium from various sources.
Simply stated, you need to absorb about 400mg +-10% of magnesium. The
calcium and magnesium malate forms in Oss Aide™ have a 85-90%
absorption efficiency and can thus deliver 350mg of calcium and 85mg of
magnesium, in addition to what is provided in your diet. See Table 1.
VITAMIN D
Oss Aide™ provides 200 IU/day or 50% the recommended daily
intake (RDI).
Women who do not get enough sun, require about 600-1,000 IU/day to maintain acceptable blood levels. Women that get some sun require 400 IU/day or less.
Because a number of people use a daily multivitamin with 200-400 IU/day and consume milk products that are fortified with Vitamin D, Oss Aide™ provides 200 IU which is complementary to other intake sources without contributing to chronic overdosing.
To prevent overloading on trace minerals, the same "complimentary source" logic was applied to Zinc, Copper and Boron doses in Oss Aide™.
FOLIC ACID
Oss Aide™ provides 800mcg of Folic acid, 200% of the RDI.
Folates are critical to health and in the US are consumed in suboptimal
amounts. The average intake is 200-350mg/day. Folates play a crucial role
in collagen and glycosaminogylcan synthesis, ie. Bone organic matrix.
Oss Aide™ provides 800mcg of Folic Acid per dose or the equivalent of 1.5 lbs of asparagus, or 1.5 lbs brussel sprouts, or 1 lb of spinach, or 10 oranges, or 10 lbs of chees, or 1.5 lbs of whole wheat. Folic acid daily intake up to 15,000mcg shows no toxicity.
Note: Folic Acid is about 1.7 times more bioavailable than dietary folates from food.
| Ingredients | Major Roles |
| Vitamin A | Regulates Bone Osteoclasts Regulates Bone Chondrocytes |
| Vitamin D | Promotes Intestinal Calcium uptake Promotes Intestinal Phosphorus uptake Promotes Kidney reabsorption of Calcium Stimulates bone turnover (both Osteoblast and Osteoclast) Enhances Osteocalcin synthesis |
| Vitamin K1 | Promotes bone formation via Osteocalcin enhancement |
| Folic Acid | Promotes cell generation and Chondrocyte activity Promotes DNA protection |
| Calcium & Magnesium Malate | Constitute the major components of bone crystalline structure Mg stimulates bone turnover |
| Copper | Enhances bone turnover |
| Zinc | Stimulates protein synthesis in bones Enhances the positive effects of soy isolates on bone |
| Boron | Enhances magnesium retention in body Down regulates phosphorus retention (May be beneficial in high protein diets) Believed to also regulate cellular respiratory processes* |
Suggested Use: Take three (3) capsules with a meal or as directed.
Caution: If pregnant, consult your physician before using this or any other product. Keep out of reach of children. Do not take this product if you have a blood disorder, are hemophiliac, or are taking medication to thin your blood
| *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. |